Test Code Mapping for GeneXpert Xpress_SARS-CoV-2_Flu_RSV ‘COVID Quad’ Panel

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This guide describes the test code mapping required to report the interpreted results (POS/NEG) for the SARSCOV2, FLUA, FLUB, and RSV tests, as well as how to send an order for the panel from your LIS/EMR. This document assumes that the Cepheid GeneXpert is configured with the default codes as shown here:

ADF Name / Assay NameADF VersionSuggested Host Order Codeb(Assay Host Test Code)Analyte Common NameSuggested GeneXpert Result Code
Xpert Xpress_SARS-CoV-2_Flu_RSV3SARSCOV2FLURSVSARS-CoV-2SARSCOV2
FLU AFLUA
FLU BFLUB
RSVRSV

For information on configuring the GeneXpert codes, see the Operator’s Manual or contact Cepheid Support.

Driver Configuration

The first step is to open Driver Properties and check Parse Interpreted Results as separate Test Code. If this is not enabled, the interpreted results will not be parsed as a test result value.

Result Code Mapping

A SARSCOV2FLURSV result message from the GeneXpert contains 31 observations, but you should only map the tests that you will be reporting. This section explains how to map the GeneXpert result codes so that you can report the interpreted results for SARSCOV2, FLUA, FLUB, and RSV.

Analyte Common NameInstrument Test Code
SARS-CoV-2SARSCOV2-Xpert Xpress_SARS-CoV-2_Flu_RSV-SARS-CoV-2-I
FLU AFLUA-Xpert Xpress_SARS-CoV-2_Flu_RSV-FLU A-I
FLU BFLUB-Xpert Xpress_SARS-CoV-2_Flu_RSV-FLU B-I
RSVRSV-Xpert Xpress_SARS-CoV-2_Flu_RSV-RSV-I

Open the Test Code Mapping window for your GeneXpert configuration and select Add. For Instrument Code enter “SARSCOV2-Xpert Xpress_SARS-CoV-2_Flu_RSV-SARS-CoV-2-I” and enter a description for the Covid test code. Select Add and then Close.

Select the newly created “SARSCOV2-Xpert Xpress_SARS-CoV-2_Flu_RSV-SARS-CoV-2-I” in the Select Instrument Test Code field. In the lower Results mapping section, select the existing Instrument Test Code, then select Remove.

In the Select or Add IM Test Code field, enter the test code for Covid used by your LIS/EMR. Change Select Test Resulting Option to Default (D). Select Add. Your screen should look like this:

Repeat the above steps to add the other three instrument test codes.

Order Code Mapping

This section explains how to add an order mapping so that you can send an order for the Xpert Xpress_SARS-CoV-2_Flu_RSV assay to the GeneXpert. It is assumed that you completed the Result Code Mapping section above.

Open the Test Code Mapping window for your GeneXpert configuration and select Add. For Instrument Code enter “SARSCOV2FLURSV” and enter a description for the COVID panel code. Select Add and then Close.

Select the newly created “SARSCOV2FLURSV” in the Select Instrument Test Code field. In the upper Orders mapping section, select the existing Instrument Test Code, then select Remove.

In the Select or Add IM Test Code box, enter the test code for Covid used by your LIS/EMR. Change ‘Select Fluid Type’ to “Other”. Click Add. Your screen should look like this:

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